CHEMBL465014


SMILES COc1ccccc1N1CCN(CCCNC(=O)c2ccc(-n3ccnc3)cc2)CC1
InChIKey RFBKHFYKBNFXJB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 419.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 7.02 7.02 7.02 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.92 6.92 6.92 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 7.02 7.02 7.02 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database