Chembl4740373

Chemical Properties

SMILES CC1N(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(=O)NCc3ccccc3Cl)cc2C12CCNCC2
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight 527.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey UASMEFJXHIESFN-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pIC50 7.57 7.57 7.57 ChEMBL
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pIC50 6.76 6.88 7.0 ChEMBL