CHEMBL474092


SMILES CC1(C)CCC(N2CCC3(CC2)C(=O)N(CCNC2CCC2)CN3c2ccccc2)c2ccccc21
InChIKey KBWCMSUFRLCWIT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 486.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.82 8.82 8.82 ChEMBL
δ OPRD Human Opioid A pKi 5.68 5.68 5.68 ChEMBL
κ OPRK Human Opioid A pKi 7.35 7.35 7.35 ChEMBL
μ OPRM Human Opioid A pKi 7.19 7.19 7.19 ChEMBL
δ OPRD Human Opioid A pKi 5.68 5.68 5.68 PDSP Ki database
NOP OPRX Human Opioid A pKi 8.82 8.82 8.82 PDSP Ki database
μ OPRM Human Opioid A pKi 7.19 7.19 7.19 PDSP Ki database
κ OPRK Human Opioid A pKi 7.35 7.35 7.35 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database