CHEMBL471980


SMILES CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CCC(C)C)cc1
InChIKey RLLSCGRLMPJHDQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 421.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 7.43 7.74 8.35 ChEMBL
μ OPRM Human Opioid A pKi 5.17 5.19 5.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pEC50 6.85 7.69 8.54 ChEMBL
CB2 CNR2 Human Cannabinoid A pIC50 7.4 7.4 7.4 ChEMBL
CB1 CNR1 Human Cannabinoid A pEC50 5.49 5.49 5.49 ChEMBL