CHEMBL448198


SMILES CCOc1ccccc1N1CCN(CC(O)CN2C(=O)N(C(C)C(=O)OC)C(=O)C2(c2ccccc2)c2ccccc2)CC1
InChIKey YVSNFTJWRKZTPD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 600.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 6.57 6.57 6.57 ChEMBL
α1B ADA1B Human Adrenoceptors A pKd 6.03 6.03 6.03 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 6.8 6.8 6.8 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.78 6.78 6.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database