CHEMBL473280


SMILES CC(C)N(CCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O)C(C)C
InChIKey OYYKUZKRRODNKD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 516.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.17 8.17 8.17 ChEMBL
δ OPRD Human Opioid A pKi 5.53 5.53 5.53 ChEMBL
κ OPRK Human Opioid A pKi 7.07 7.07 7.07 ChEMBL
μ OPRM Human Opioid A pKi 7.09 7.09 7.09 ChEMBL
δ OPRD Human Opioid A pKi 5.53 5.53 5.53 PDSP Ki database
κ OPRK Human Opioid A pKi 7.07 7.07 7.07 PDSP Ki database
μ OPRM Human Opioid A pKi 7.09 7.09 7.09 PDSP Ki database
NOP OPRX Human Opioid A pKi 8.17 8.17 8.17 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database