CHEMBL473701


SMILES CCN(CC)CCN1CN(c2ccccc2)C2(CCN(Cc3c(Cl)cccc3Cl)CC2)C1=O
InChIKey PBHBYYYIKRUVKK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 488.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.0 9.0 9.0 ChEMBL
δ OPRD Human Opioid A pKi 6.42 6.42 6.42 ChEMBL
κ OPRK Human Opioid A pKi 7.25 7.25 7.25 ChEMBL
μ OPRM Human Opioid A pKi 6.91 6.91 6.91 ChEMBL
NOP OPRX Human Opioid A pKi 9.0 9.0 9.0 PDSP Ki database
δ OPRD Human Opioid A pKi 6.42 6.42 6.42 PDSP Ki database
κ OPRK Human Opioid A pKi 7.25 7.25 7.25 PDSP Ki database
μ OPRM Human Opioid A pKi 6.91 6.91 6.91 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database