CHEMBL4747770


SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CNC(=O)C2CCN(c3oc(C)nc3C#N)CC2)cc1
InChIKey HIFRVQKIYMYVQE-PGUFJCEWSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 3
Rotatable bonds 14
Molecular weight (Da) 725.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pKi 8.18 8.18 8.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pEC50 8.09 8.09 8.09 ChEMBL