Chembl4756711

Chemical Properties

SMILES CC[C@](C)(O)c1nc([C@@H]2CC[C@@H](C)N(C(=O)c3cscc3-n3nccn3)C2)oc1C
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight 429.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey QIFHYQSASFBJSW-VWLHBSKXSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pIC50 5.01 5.01 5.01 ChEMBL
OX2 OX2R Human Orexin A pIC50 7.75 7.75 7.75 ChEMBL