CHEMBL4526012


SMILES Cn1cncc1-c1c[nH]c2ccc(Br)cc12
InChIKey NGEGVUWXHYDOQM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 275.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.61 6.61 6.61 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.03 5.03 5.03 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.91 5.91 5.91 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.73 5.73 5.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database