CHEMBL4753657


SMILES COc1ccc(N2CCOCC2)c2sc(NC(=O)N3CCC(CF)CC3)nc12
InChIKey FFLSMIVBQPLWHK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 408.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Rat Adenosine A pKi 7.69 7.69 7.69 ChEMBL
A2A AA2AR Human Adenosine A pKi 8.44 8.44 8.44 ChEMBL
A1 AA1R Human Adenosine A pKi 5.92 5.92 5.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database