Chembl4778604

Chemical Properties

SMILES CCCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N1CCC[C@H]1C(=O)O)C(C)C
Hydrogen bond acceptors 14
Hydrogen bond donors 13
Rotatable bonds 31
Molecular weight 1211.7

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey WJXARWOCMOVEEV-CUZNLEPHSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
apelin APJ Human Apelin A pKi 7.68 7.68 7.68 ChEMBL
apelin APJ Human Apelin A pEC50 5.98 6.63 7.64 ChEMBL