CHEMBL4558031


SMILES O=C1c2ccc(F)cc2CC1CCN1CCCN(c2ccc(Cl)cn2)CC1
InChIKey IKFBJNOEPLDTAT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 387.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.24 7.24 7.24 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.44 7.44 7.44 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.45 6.45 6.45 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.9 6.9 6.9 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.88 7.88 7.89 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.68 6.68 6.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.44 6.44 6.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database