CHEMBL456225


SMILES O=C1N(CCNC2CCCC2)CN(c2ccccc2)C12CCN(C(c1ccccc1Cl)c1ccccc1Cl)CC2
InChIKey SBLIYIIALWZVLS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 576.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.06 8.06 8.06 ChEMBL
δ OPRD Human Opioid A pKi 5.82 5.82 5.82 ChEMBL
κ OPRK Human Opioid A pKi 6.61 6.61 6.61 ChEMBL
NOP OPRX Human Opioid A pKi 8.06 8.06 8.06 PDSP Ki database
δ OPRD Human Opioid A pKi 5.82 5.82 5.82 PDSP Ki database
κ OPRK Human Opioid A pKi 6.61 6.61 6.61 PDSP Ki database
μ OPRM Human Opioid A pKi 6.2 6.2 6.2 PDSP Ki database
μ OPRM Human Opioid A pKi 6.2 6.2 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database