GR 175737


SMILES Clc1ccc(cc1)Cc1noc(n1)CCc1cnc[nH]1
InChIKey CPOUJACQGWJJQB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 288.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 8.3 8.3 8.3 Guide to Pharmacology
H3 HRH3 Rat Histamine A pKi 8.15 8.32 8.6 ChEMBL
H3 HRH3 Human Histamine A pKi 8.6 8.6 8.6 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database