Chembl4798102

Chemical Properties

SMILES O=C(c1cccn2ccnc12)N1CCC(F)(F)[C@@H](Oc2ccc3ccccc3n2)C1
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight 408.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey OAATXFVQEMAHDA-SFHVURJKSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 8.74 8.74 8.74 ChEMBL
OX2 OX2R Human Orexin A pKi 6.0 6.0 6.0 ChEMBL