Chembl4798102
Chemical Properties
| SMILES | O=C(c1cccn2ccnc12)N1CCC(F)(F)[C@@H](Oc2ccc3ccccc3n2)C1 |
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 3 |
| Molecular weight | 408.1 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | OAATXFVQEMAHDA-SFHVURJKSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| OX1 | OX1R | Human | Orexin | A | pKi | 8.74 | 8.74 | 8.74 | ChEMBL |
| OX2 | OX2R | Human | Orexin | A | pKi | 6.0 | 6.0 | 6.0 | ChEMBL |