CHEMBL458342


SMILES Clc1ccc(N2CCC3CCC(C2)N3Cc2c[nH]c3ncccc23)cc1
InChIKey UPZQTOBGZYRXMC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.23 6.23 6.23 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.47 6.47 6.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.47 6.47 6.47 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 6.23 6.23 6.23 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database