CHEMBL4790020


SMILES Cc1c(S(=O)(=O)N[C@H]2CCN(CCCc3noc4ccccc34)C2)sc2ccc(Cl)cc12
InChIKey WVWFPNBJDFSYGW-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 489.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.66 6.66 6.66 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.41 7.41 7.41 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.05 8.05 8.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database