CHEMBL4595266


SMILES CCCN(CCCCNC(=O)c1ccc(-c2ccccn2)cc1)CC1CC1c1cc(F)ccc1OC
InChIKey OHSIGBOKYLDSHG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 13
Molecular weight (Da) 489.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.94 5.94 5.94 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.75 5.75 5.75 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.5 5.5 5.5 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.4 8.4 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database