CHEMBL4595727


SMILES COc1ccc(F)cc1C1CC1CNCCCSc1nnc(-c2ccccc2)n1C
InChIKey PLZGEHCHVFNRGK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 6.03 6.03 6.03 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.88 6.88 6.88 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.2 6.2 6.2 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.05 7.05 7.05 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.6 6.6 6.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database