CHEMBL4596409


SMILES CN[C@@H]1CCN(c2ccnc(NCC(C)(C)C)n2)C1
InChIKey ZZPQCQWVWDUPSI-LLVKDONJSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 263.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 8.42 8.42 8.42 ChEMBL
H3 HRH3 Human Histamine A pKi 7.56 7.56 7.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 7.59 8.28 8.96 ChEMBL
H4 HRH4 Rat Histamine A pEC50 7.53 8.37 9.21 ChEMBL
H4 HRH4 Human Histamine A pEC50 8.16 8.69 9.22 ChEMBL