CHEMBL4596514


SMILES CCCN(CCCCNC(=O)c1cc2ccccc2[nH]1)C[C@@H]1C[C@H]1c1cccc(Cl)c1Cl
InChIKey OXKMARLXXNQVMY-PZJWPPBQSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 471.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.98 5.98 5.98 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.86 5.86 5.86 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.29 6.29 6.29 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.66 8.66 8.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.27 6.27 6.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 7.06 7.06 7.06 ChEMBL