CHEMBL4596929


SMILES CCCN(CCCCNC(=O)c1ccc2ccccc2c1)C[C@@H]1C[C@H]1c1cccc(Cl)c1Cl
InChIKey KFWJKLDOLDILRK-UKILVPOCSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 482.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.09 6.09 6.09 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.89 5.89 5.89 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.37 6.37 6.37 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.36 8.36 8.36 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.17 6.17 6.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 4.79 4.79 4.79 ChEMBL
D3 DRD3 Human Dopamine A pEC50 6.75 6.75 6.75 ChEMBL