CHEMBL4597532


SMILES COc1ccc(F)cc1C1CC1CN(CCCSc1nnc(-c2ccccc2)n1C)CC1CC1
InChIKey WZYFZOQYIYKUJN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 12
Molecular weight (Da) 480.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.92 5.92 5.92 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.54 6.54 6.54 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.9 6.9 6.9 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.19 7.19 7.19 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.97 5.97 5.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database