CHEMBL1180627


SMILES Oc1cc2c(cc1Cl)CC[C@H](CNCc1ccccc1)O2
InChIKey BCTPODDQZONFKA-CQSZACIVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 303.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 8.66 8.94 9.22 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.06 8.06 8.06 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.67 6.67 6.67 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.47 8.47 8.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.15 8.15 8.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database