CHEMBL484102


SMILES COc1ccccc1N1CCN(CC(O)CN2C(=O)N(C)C(=O)C2(c2ccccc2)c2ccccc2)CC1
InChIKey VDYXCGVNXROZOL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 514.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 6.85 6.85 6.85 ChEMBL
α1B ADA1B Human Adrenoceptors A pKd 6.02 6.02 6.02 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 6.8 6.8 6.8 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.79 6.79 6.79 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database