CHEMBL1180636


SMILES Oc1ccc2c(c1)O[C@H](CN1CCc3ccccc3C1)CC2
InChIKey IWUPLAFLTUWLMF-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.96 7.18 7.4 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.54 6.54 6.54 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.0 9.0 9.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.13 7.13 7.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database