CHEMBL4845947


SMILES O=C1CCc2cc(C(=O)CCCN3CCN(c4ccccn4)CC3)ccc2N1
InChIKey NFCAJYXEMNIWPF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 378.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.32 8.32 8.32 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.33 6.36 6.39 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.3 7.31 7.33 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.5 5.5 5.51 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.4 6.41 6.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database