CHEMBL484599


SMILES CCCN1CCO[C@@H]2c3cc(C(N)=O)ccc3CC[C@H]21
InChIKey XKTRZPQOQOCNJU-HUUCEWRRSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 274.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 7.83 7.83 7.83 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.92 5.92 5.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pIC50 8.38 8.38 8.38 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 6.39 6.39 6.39 ChEMBL
D2 DRD2 Rat Dopamine A pEC50 7.3 7.3 7.3 ChEMBL
D3 DRD3 Human Dopamine A pEC50 8.64 8.64 8.64 ChEMBL