CHEMBL4850490


SMILES Cc1nc(N)sc1CCCN/C(N)=N/C(=S)NC[C@H](C)c1ccccc1
InChIKey VCBVQPPOGCHJKE-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 7
Molecular weight (Da) 390.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 4.35 4.35 4.35 ChEMBL
H1 HRH1 Human Histamine A pKi 4.2 4.2 4.2 ChEMBL
H3 HRH3 Human Histamine A pKi 4.16 4.16 4.16 ChEMBL
H2 HRH2 Human Histamine A pKi 5.94 5.94 5.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database