CHEMBL46395


SMILES O=C(O)CCCCCCN1C(=O)CC[C@@H]1CC[C@@H](O)Cc1cccc(C(F)(F)F)c1
InChIKey BGIIQHLOAQSIFC-RBUKOAKNSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight (Da) 429.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Human Prostanoid A pKi 4.42 4.42 4.42 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 7.8 7.8 7.8 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 4.66 4.66 4.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Rat Prostanoid A pEC50 7.89 7.89 7.89 ChEMBL
EP4 PE2R4 Rat Prostanoid A pIC50 7.68 7.68 7.68 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 6.34 6.34 6.34 ChEMBL