CHEMBL4856572


SMILES Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCC(c1ccccc1)C(C)C
InChIKey GFABJVBAIQBMNP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 8
Molecular weight (Da) 402.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 5.23 5.23 5.23 ChEMBL
H2 HRH2 Human Histamine A pKi 6.99 6.99 6.99 ChEMBL
H1 HRH1 Human Histamine A pKi 5.23 5.23 5.23 ChEMBL
H3 HRH3 Human Histamine A pKi 4.93 4.93 4.93 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pEC50 6.8 7.15 7.51 ChEMBL