CHEMBL4645525


SMILES O=S(=O)(NCCCCCCN1CCN(c2nsc3ccccc23)CC1)c1ccc2ccccc2c1
InChIKey URZRGOOTISGVOW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 508.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.24 7.24 7.24 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.36 7.36 7.36 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.14 7.14 7.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.57 7.57 7.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database