Ligand Data

Ligand

id 1848
Name ICI198615
SMILES COc1cc(ccc1Cn1ncc2c1cc(cc2)NC(=O)OC1CCCC1)C(=O)NS(=O)(=O)c1ccccc1
InChIKey YRCPIXCRSAKRGM-UHFFFAOYSA-N
Type small-molecule
External Links

Structure

Properties

Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight 548.2


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
CysLT1 CLTR1 Guinea pig Leukotriene A (Rhodopsin) 0.3 15050.1 30100.0