CHEMBL4648071


SMILES O=C(Nc1ccc(F)cc1-c1cccc(Cl)c1)O[C@H]1CN2CCC1CC2
InChIKey OUUOAZNFNHOROT-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 374.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.41 9.41 9.41 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.51 7.51 7.51 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 9.28 9.28 9.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pEC50 7.57 7.67 7.77 ChEMBL