CHEMBL127317


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3n2)CC1
InChIKey CDDVHWKFFCJTOZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 418.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.32 8.32 8.32 ChEMBL
D1 DRD1 Rat Dopamine A pKi 5.87 5.87 5.87 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.08 7.08 7.08 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.18 8.32 8.46 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.17 7.22 7.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database