CHEMBL4865907


SMILES CN1CCN(Cc2ccc(OCCCN3CCC(c4noc5cc(F)ccc45)CC3)cc2)CC1
InChIKey MVVKKFHFADVKMW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 466.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 6.48 6.48 6.48 ChEMBL
H1 HRH1 Human Histamine A pKi 6.14 6.14 6.14 ChEMBL
H3 HRH3 Human Histamine A pKi 8.09 8.09 8.09 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.03 7.03 7.03 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.24 6.24 6.24 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.33 8.33 8.33 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.63 7.63 7.63 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.77 8.77 8.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database