CHEMBL466847


SMILES OC1(c2ccccc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl
InChIKey FRMIDCOICRIAHB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 437.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.47 8.47 8.47 ChEMBL
δ OPRD Human Opioid A pKi 5.5 5.5 5.5 ChEMBL
κ OPRK Human Opioid A pKi 6.96 6.96 6.96 ChEMBL
μ OPRM Human Opioid A pKi 7.66 7.66 7.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pEC50 6.47 6.47 6.47 ChEMBL