CHEMBL468711


SMILES c1cncc(-c2ccccc2[C@@H]2Cc3nccn3C2)c1
InChIKey JVQZWPGHLBOWKN-CQSZACIVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 261.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 6.0 6.0 6.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pEC50 6.12 6.12 6.12 ChEMBL
α1D ADA1D Human Adrenoceptors A pEC50 6.92 6.92 6.92 ChEMBL
α1A ADA1A Human Adrenoceptors A pEC50 9.0 9.0 9.0 ChEMBL