CHEMBL472669


SMILES O=C1N(CCNCC2CC2)CN(c2ccccc2)C12CCN(Cc1c(Cl)cccc1Cl)CC2
InChIKey HFUHBOZRXJGZGY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 486.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.3 9.3 9.3 ChEMBL
δ OPRD Human Opioid A pKi 6.35 6.35 6.35 ChEMBL
κ OPRK Human Opioid A pKi 7.6 7.6 7.6 ChEMBL
μ OPRM Human Opioid A pKi 7.05 7.05 7.05 ChEMBL
NOP OPRX Human Opioid A pKi 9.3 9.3 9.3 PDSP Ki database
δ OPRD Human Opioid A pKi 6.35 6.35 6.35 PDSP Ki database
κ OPRK Human Opioid A pKi 7.6 7.6 7.6 PDSP Ki database
μ OPRM Human Opioid A pKi 7.05 7.05 7.05 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database