CHEMBL4878587


SMILES COc1cc2c(cc1OC)CN(Cc1ccccc1CNC(=O)c1ccc(C#N)cc1)CC2
InChIKey CLAAZMXUBMWYHD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 441.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 6.47 6.47 6.47 ChEMBL
D1 DRD1 Human Dopamine A pKi 7.24 7.24 7.24 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.85 6.85 6.85 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.47 8.47 8.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.3 7.3 7.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database