CHEMBL4870716


SMILES Fc1ccc2c(C3CCN(CCCOc4ccc(CN5CCOCC5)cc4)CC3)noc2c1
InChIKey WQWHPPMEWVYOCN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 453.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 6.78 6.78 6.78 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.36 8.36 8.36 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.07 7.07 7.07 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.82 8.82 8.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database