CHEMBL473884


SMILES O=C1N(CCO)CN(c2ccccc2)C12CCN(C(c1ccccc1Cl)c1ccccc1Cl)CC2
InChIKey CIMPTCWBNSBNEP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 509.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.73 7.73 7.73 ChEMBL
δ OPRD Human Opioid A pKi 5.25 5.25 5.25 ChEMBL
κ OPRK Human Opioid A pKi 5.76 5.76 5.76 ChEMBL
μ OPRM Human Opioid A pKi 6.32 6.32 6.32 ChEMBL
NOP OPRX Human Opioid A pKi 7.73 7.73 7.73 PDSP Ki database
δ OPRD Human Opioid A pKi 5.25 5.25 5.25 PDSP Ki database
κ OPRK Human Opioid A pKi 5.76 5.76 5.76 PDSP Ki database
μ OPRM Human Opioid A pKi 6.32 6.32 6.32 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database