CHEMBL127828


SMILES CN1c2ccccc2C(c2ccccc2F)=NCC1CCNC(=O)c1ccsc1
InChIKey AVUSYTRJVKZPGP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 407.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 9.11 9.11 9.11 ChEMBL
δ OPRD Human Opioid A pKi 7.16 7.49 7.82 ChEMBL
κ OPRK Human Opioid A pKi 9.43 9.43 9.43 ChEMBL
μ OPRM Human Opioid A pKi 8.52 8.52 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database