CHEMBL474096


SMILES CCCCNCCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O
InChIKey ZBXWZLGBCKBMLA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 488.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.3 9.3 9.3 ChEMBL
δ OPRD Human Opioid A pKi 5.4 5.4 5.4 ChEMBL
κ OPRK Human Opioid A pKi 6.86 6.86 6.86 ChEMBL
μ OPRM Human Opioid A pKi 7.18 7.18 7.18 ChEMBL
NOP OPRX Human Opioid A pKi 9.3 9.3 9.3 PDSP Ki database
κ OPRK Human Opioid A pKi 6.86 6.86 6.86 PDSP Ki database
μ OPRM Human Opioid A pKi 7.18 7.18 7.18 PDSP Ki database
δ OPRD Human Opioid A pKi 5.4 5.4 5.4 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database