CHEMBL487476
SMILES | O=C(NC[C@@H](O)C(=O)O)c1ccc(CN(C(=O)Nc2cc(Cl)cc(Cl)c2)c2ccc(C3=CCCCC3)cc2)cc1 |
InChIKey | XNSJRSAITGCUKS-HHHXNRCGSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 4 |
Rotatable bonds | 9 |
Molecular weight (Da) | 581.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
glucagon | GLR | Human | Glucagon | B1 | pKi | 7.07 | 7.07 | 7.07 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GIP | GIPR | Rat | Glucagon | B1 | pIC50 | 6.3 | 6.3 | 6.3 | ChEMBL |
glucagon | GLR | Rat | Glucagon | B1 | pIC50 | 7.37 | 7.37 | 7.37 | ChEMBL |
GIP | GIPR | Human | Glucagon | B1 | pIC50 | 6.45 | 6.45 | 6.45 | ChEMBL |
glucagon | GLR | Human | Glucagon | B1 | pIC50 | 8.41 | 8.41 | 8.41 | ChEMBL |
GLP-1 | GLP1R | Human | Glucagon | B1 | pIC50 | 4.77 | 4.77 | 4.77 | ChEMBL |