Chembl511655


SMILES O=C(/C=C/c1ccccc1Cl)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5
InChIKey NAALUTWMVSSPHM-ODWVLBEOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 5
Molecular weight (Da) 506.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pEC50 7.92 7.92 7.92 ChEMBL
μ OPRM Rat Opioid A pKi 10.1 10.1 10.1 ChEMBL
κ OPRK Human Opioid A pEC50 9.4 9.4 9.4 ChEMBL
κ OPRK Human Opioid A pKi 9.57 9.57 9.57 ChEMBL