Chembl513598


SMILES COc1ccccc1/C=C/C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5
InChIKey FNPUPASPXRTPGG-PILMVFDPSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 502.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pEC50 8.68 8.68 8.68 ChEMBL
μ OPRM Rat Opioid A pKi 10.07 10.07 10.07 ChEMBL
κ OPRK Human Opioid A pEC50 9.02 9.02 9.02 ChEMBL
κ OPRK Human Opioid A pKi 9.47 9.47 9.47 ChEMBL