CHEMBL489126


SMILES COc1cccc(-n2c(=O)n(Cc3c(F)cccc3F)c3cnc(NC4CC4)nc32)c1
InChIKey DJEOUFPKQANXEL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 423.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Human Adenosine A pKi 8.4 8.4 8.4 ChEMBL
A1 AA1R Human Adenosine A pKi 6.63 6.63 6.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database