CHEMBL494982


SMILES CC1CC(C)(C)N=C(c2cccc(Cc3c[nH]cn3)c2)O1
InChIKey APQJKSFOISLQFF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 283.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Guinea pig Histamine A pKd 8.4 8.4 8.4 ChEMBL
H4 HRH4 Human Histamine A pKi 8.08 8.08 8.08 ChEMBL
H3 HRH3 Human Histamine A pKi 8.9 8.9 8.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pEC50 8.7 8.7 8.7 ChEMBL